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Year : 2018  |  Volume : 5  |  Issue : 2  |  Page : 75-80

Aortic blood pressure and central hemodynamics measured by noninvasive pulse wave analysis in Gujarati normotensives

Department of Physiology, Government Medical College, Bhavnagar, Gujarat, India

Correspondence Address:
Dr. Jayesh Dalpatbhai Solanki
F1, Shivganga Appartments, Plot No 164, Bhayani Ni Waadi, Opp. Bawaliya Hanuman Temple, Gadhechi Wadlaa Road, Bhavnagar - 364 001, Gujarat
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijcep.ijcep_24_18

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Background and Aim: Central blood pressure (BP) and central hemodynamics are immediate and discrete parameters inferring about the cardiovascular system. They can be studied noninvasively by pulse wave analysis (PWA). Before use, these parameters need normative baseline study to set reference values. Methods: We conducted a cross-sectional study in 900 normotensives, aged 15–65 years (divided into five subgroups). Oscillometric PWA was accomplished by Mobil-O-Graph (IEM, Germany). Aortic BP, cardiac output (CO) and index, peripheral resistance, stroke volume and index, stroke work, difference between brachial and aortic systolic, and pulse pressure were the studied parameters. They were analyzed further with respect to subgroup based on age, gender, and body mass index (BMI). Multiple regressions were done to find significant predictors of central hemodynamics. P < 0.05 was taken as statistical significance. Result: There were five age-based subgroups from 15 to 65 years, showing increase in central BP- and CO-related parameters age. Males had significantly higher results than females except heart rate (HR) and peripheral resistance. BMI ≥23 was related to significantly higher results. Age, HR, height, weight, and BMI were not significant predictors of PWA parameters. Central hemodynamics were predicted by brachial BPs, systolic and diastolic more than mean or pulse. Conclusion: It is feasible to assess central hemodynamics by PWA. Age, gender, BMI, HR, and brachial pressure affect the central hemodynamics in normotensive individuals. These baseline data can be referred for the future studies in our population.

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