Efficacy of Apricot Kernel Decoction on Salivary Sialic Acid Level in Periodontitis
Background and Aim: This study was designed to explore the clinical utility of apricot kernel decoction on salivary glycoproteins in patients with periodontitis. Methods: The salivary samples were obtained from 123 subjects divided into 4 groups, namely healthy individuals (healthy), non-treated patients with periodontitis (control), chlorhexidine-treated patients with periodontitis (chlorhexidine) and both decoction and chlorhexidine-treated patients with periodontitis (decoction + chlorhexidine). Salivary sialic acid level was measured by means of Surface Enhanced Raman Spectroscopy (SERS). Calculus and gingival Index were evaluated by means of Greene and Vermillion and Löe. Results: The values of salivary sialic acid in decoction + chlorhexidine group were significantly lower than chlorhexidine group (P<0.05) and control group (P<0.01). On the other hand, in decoction+ chlorhexidine group, Calculus and Gingival Index decreased significantly compared with control group and chlorhexidine group (P<0.01, P<0.05, respectively). Conclusion: Our data suggest that decoction of apricot kernel can be used as mouthwash for the treatment in periodontitis.